DNA 30

Johns Hopkins University

September 16-20, 2024

Program

Invited Speakers

Julius B. Lucks

Professor Chemical and Biological Engineering

Northwestern University

Clifford P. Brangwynne

Chemical and Biological Engineering

Princeton University

Andrea Liu

Theoretical Soft and Living Matter Physicist

Kate Adamala

McKnight Land Grant Assistant Professor

University of Minnesota

Thomas Ouldridge

Imperial College London

Conference Program

Day 1 (September 16, 2024) Scott-Bates Commons 3301 N Charles St, Baltimore, MD 21218

 (Session chairs: Morning session: Andrew Turberfield.  Afternoon session: Lulu Qian) 

8:20 

Check-in, Breakfast 

8:50-9:00 

Opening remark 

9:00-10:00 

KEYNOTE TALK (Julius B. Lucks: How do RNAs fold dynamically? Finding and utilizing strand displacement in biology and biotechnology.) 

10:00-10:15 

Break 

10:15-10:45 

TRACK B: Paul Cunningham, Sara Ansteatt, Adam Meares, Sebastian Diaz, Young Kim, Igor Medintz and Joseph Melinger: Dye dimer geometry control through linker length to DNA scaffoldtrc

10:45-11:15 

TRACK B: Tianqi Song and Lulu Qian: Sustainable computation in heat powered DNA logic circuits and neural networks

11:15-11:45 

TRACK B: Alexander Dack, Benjamin Qureshi, Thomas E. Ouldridge and Tomislav Plesa: Recurrent neural chemical reaction networks that approximate arbitrary dynamics

11:45-12:00 

TRACK C: Qi Yang, Xu Chang and Fei Zhang: Angle-Controllable RNA Tiles for Programable Array Assembly and RNA Sensing

12:00-13:30 

Lunch  

13:30-14:30 

KEYNOTE TALK: (Thomas Ouldridge: DNA strand displacement – a uniquely engineerable reaction mechanism) 

14:30-15:00 

TRACK A: Matthew R. Lakin and Sarika Kumar: Geometric enumeration of localized DNA strand displacement reaction networks

15:00-15:15 

TRACK C: Mahdi Dizani, Daniela Sorrentino, Siddharth Agarwal, Jaimie Stewart and Elisa Franco: Protein recruitment to dynamic DNA-RNA host condensates

15:15-15:30 

Break 

15:30-16:00 

TRACK A: Erik D. Demaine, Timothy Gomez, Elise Grizzell, Markus Hecher, Jayson Lynch, Robert Schweller, Ahmed Shalaby and Damien Woods: Domain-Based Nucleic-Acid Minimum Free Energy: Algorithmic Hardness and Parameterized Bounds

15:45-16:15 

TRACK B: Anthony Vetturini, Jonathan Cagan and Rebecca Taylor: Design exploration of wireframe DNA origami through multiobjective optimization-driven generative design

16:30-16:45 

Track B: Trent Rogers, Constantine Evans and Damien Woods: A 1D nanoscale printer: assembling DNA nanotubes of arbitrary and precise length from a fixed DNA tile set

16:45-17:00 

 Break

17:00-19:00

Poster Session 1

  

Day 2 (September 17, 2024) Scott-Bates Commons 3301 N Charles St, Baltimore, MD 21218

(Session chairs: Morning session: Matthew Lakin. Afternoon session: Fei Zhang)

8:20 

Breakfast 

9:00-10:00 

KEYNOTE TALK: (Andrea Liu: Designing function in adaptive matter) 

10:00-10:15 

Break 

10:15-10:45 

TRACK A: Phillip Drake, Daniel Hader and Matthew Patitz: Simulation of the abstract Tile Assembly Model Using Crisscross Slats

10:45-11:15 

TRACK A: Antti Elonen and Pekka Orponen: Designing 3D RNA origami nanostructures with a minimum number of kissing loops

11:15-11:45 

TRACK A: Cameron Chalk, Salvador Buse, Krishna Shrinivas, Arvind Murugan and Erik Winfree: Learning and inference in a lattice model of many-component condensates

11:45-12:00 

TRACK C: Jinsu Kim and Sunghwa Kang: Noise-robust neural network trained by chemical reactions

12:00-13:30 

Lunch  

13:30-14:30 

KEYNOTE TALK: (Kate Adamala: Law of thought, in synthetic cells) 

14:30-15:00 

TRACK B: Jordan Janowski, Van A.B. Pham, Simon Vecchioni, Natasha Jonoska and Ruojie Sha: Engineering tertiary chirality in helical biopolymers

15:00-15:15 

TRACK C: Yixuan Lee and Ho-Lin Chen: Simulation Power of Freezing Surface Chemical Reaction Networks

15:15-15:30 

Break 

15:30-16:00 

TRACK B: Thong Diep, Hao Liu, Petr Sulc, Michael Matthies and Joshua Evans: DNA polycubes: A general 3D nanoscale assembly platform

16:00-16:30 

TRACK B: Joshua Evans and Petr Sulc: Design and Simulation of Self-Assembling Systems with Signal-Passing Particles

16:30-16:45 

TRACK C: Kim Calabrese and David Doty: Rate-independent continuous inhibitory chemical reaction networks are Turing-universal

16:45-17:00 

Break  

17:00-19:00 

Poster Session 2

  

Day 3 (September 18, 2024)Scott-Bates Commons 3301 N Charles St, Baltimore, MD 21218

(Session chairs: Morning session: Erik Winfree. Afternoon session: Nicolas Schanabel) 

8:20 

Breakfast 

9:00-10:00 

KEYNOTE TALK: (Clifford P. Brangwynne: Engineering organelles, one drop at a time) 

10:00-10:15 

Break 

10:15-10:45 

TRACK B: Samuel Schaffter: Genetically encoded RNA strand exchange circuits for programmable protein expression and computation in bacteria

10:45-11:15 

TRACK B: Heon Joon Lee, Samuel W. Schaffter and Rebecca Schulman: Designing modular and tunable protein biosensors using aptamer-regulated transcription

11:15-11:45 

TRACK B: Bjorn Hogberg: An Autonomous Robotic Switch for Logic-gated Presentation of Cytotoxic Ligand Patterns in vivo

11:45-12:00 

Track C: Sreelakshmi Meppat and Shelley Wickham: Barrel-encapsulated DNA Nanopores with independent control of membrane docking and transport

12:00-13:30 

Lunch 

13:30-15:30 

Poster Session 3 

15:30-15:45 

Break 

15:45-16:15 

TRACK B: Constantine Evans, Jackson O’Brien, Erik Winfree and Arvind Murugan: Pattern recognition in the nucleation kinetics of non-equilibrium self-assembly

16:15-16:45 

TRACK B: Ryan Krueger, Megan Engel, Ryan Hausen, Edward Hunter and Michael Brenner: Energy Functions as Policies

16:45-17:15 

TRACK B: Hao Liu, Michael Matthies, Thong Diep, Hao Yan and Petr Sulc: Inverse design of DNA origami superlattices through model-driven experiments

17:15-17:45 

TRACK B: Boya Wang, Cameron Chalk, David Doty and David Soloveichik: Molecular computation at equilibrium via programmable entropy

17:45-18:00 

Closing Remark 

Day 4 (September 19, 2024) Scott-Bates Commons 3301 N Charles St, Baltimore, MD 21218

(Session chairs: Morning session: William Shih)

8:20 Breakfast 
8:45-10:00 TULIP AWARD KEYNOTE TALK:  
10:00-10:15 Break 
10:15-10:45 TRACK B: Tiernan Kennedy, Thomas Mayer, Friedrich Simmel and Chris Thachuk: Systematic incorporation of non-natural base pairs for robust strand displacement in complex environments
10:45-11:15 TRACK B: Salvador Buse and Erik Winfree: Developmental Pattern Formation in Neural Reaction-Diffusion Systems
11:15-11:20Short Presentaion: Art of Molecular Programming (AoMP)
11:20-11:25Short Presentation: Molpigs (Molecular Programming Interest Group)
11:30-11:45 Group Photo 
17:00-19:00 Evergreen Museum tours  4545 N Charles St, Baltimore, MD 21210 (excursion) 
19:00- 

Conference Dinner (at Evergreen Museum following museum tour) 

Conference Dinner (at Evergreen Museum following museum tour) 
7-7:40 Dinner
7:40-7:45 Organizing Committee Thank You
7:45-7:55 Memorial for Yan Liu
8:00-8:15 Student Poster and Presentation awards
8:20-8:25 Thanks to Steering Committee, Staff, Student Volunteers
8:25-8:30 Preview of DNA 31

  

Day 5 (September 20, 2024) Scott-Bates Commons 3301 N Charles St, Baltimore, MD 21218

  

8:00-15:00 

Computational Materials Design and Biosensing Using Nucleic Acids- Workshop. Register Here